Sepulcher is the first boss monster encountered in Silent Hill: Homecoming. He is the manifestation of Sam Bartlett's guilt over murdering his son Joey Bartlett, whom he buried alive in the garden of the Grand Hotel as a sacrifice to maintain the pact with the Order and their god.
Sepulcher appears when Alex Shepherd finds Sam Bartlett in the Otherworld Grand Hotel. After presenting him with Joey's watch, Bartlett throws it away and it sinks into the ground. The tree behind them then uproots itself revealing it to be Sepulcher. Mayor Bartlett pleads with the Order's god to have mercy on him, but in response Sepulcher slams his hand down on him, crushing him with a single blow.
Afterwards, he is promptly defeated by Alex, who then blacks out and returns to Shepherd's Glen.
Sepulcher appears as a gigantic cross between a corpse and a monstrous tree. His whole body hangs from the ceiling, and his bloated underside resembles a destroyed trunk of a tree, with bits of bodies hanging out of it. His "trunk" is connected by hooks to several bodies that are wrapped in cocoon-like sacks of flesh. He supports himself with his long arms and large hands, he only has three fingers with four fingernails, which he also uses to attack. His face is dominated by a root-like, fleshy tumor.
When he is dismounted from the ceiling, he will crawl on his arms and drag the rest of his body behind him. The skin on his arms are stretched thin, reminiscent of a decomposing corpse. The oozing growth over his mouth could also represent Joey's suffocation while buried alive, the tumor-like growth also bears a resemblence to Amnion's umbilical cord.
Sepulcher's size and mass afford him enough strength to smash a man flat with a single strike. In his first phase, Sepulcher attacks using his massive arms and by shaking debris from the ceiling to damage Alex Shepherd. Alex can take cover behind the several bookcases in the room, however, the monster will break these after enough hits. In the spaces between the bookcases, there are several fleshy sacks surrounding the Sepulcher. These must be attacked enough that they recede up into the ceiling. The number of fleshy sacks varies depending on the game's difficulty setting.
After all the fleshy sacks have been destroyed, Sepulcher drops from the ceiling. He can be stunned with a melee or ranged attack, which is the perfect time to attack him. However, in both forms, his arms do a large amount of damage, and when on the ground, he can grab Alex to crush him, killing him. To avoid damage, it is recommended that Alex not attack his center. Striking Sepulcher's arms with a melee weapon will cause him to fall, allowing Alex to unleash a chain of attacks on the monstrosity.
Sepulcher is, at least by assumption, a physical manifestation of Mayor Bartlett's guilt over his son Joey's murder. He was sacrificed via suffocation while being buried alive. The garden in which the creature is encountered was where Joey was buried, and then he rises from the hole as a larger-than-life monster with a dark, oozing gag in its mouth, which may be Joey's corpse. Its body is at first encased in the bag Joey was buried in, and all of the bags around him represent him as well. When buried, Sepulcher's backside looks very plant-like, which reflects Joey's adoration for plants.
- Sepulchre (from Latin "sepulchrum" literally meaning "tomb") is a cavernous tomb, and according to Christianity, Jesus Christ was buried in a sepulchre before being resurrected three days later. This is where Sepulcher got its name and most likely links Sepulcher to Joey's murder, since Joey was buried alive in the same way that Jesus simply put can be said to have been.
- "Vivisepulture" is the term used for someone who has been buried alive. The "Vivi" part means "alive", while the "Sepulture" part means "tomb" or "burial". Although the spelling is slightly different, the connections are clear between the term for Joey's sacrifice and the monster's name.
- When Sepulcher crushes Alex, he will stand up if he has been hit with a non-fatal attack.
- Defeating Sepulcher in the Xbox 360 version unlocks the Achievement "Six Feet Under".
- The name Joey is etymologically linked to the name Joshua; Joey is a derivative of the name Joseph or Yeosheph which means Yehova (God) will add (Joey was added to the earth), while Joshua is a derivative of the Hebrew name Yeoshua, meaning literally "Jehova will strike". This may symbolize that, through the monsters, the Order's god is striking at the residence of Shepherd's Glen as punishment for their failure to uphold the contracts.