The Saint Medallion is an item obtainable in Silent Hill 4: The Room. Its aura repels all supernatural phenomena including ghosts, wheelchairs and the Hauntings that occur in Room 302. When held in the presence of a ghost, its movement will become slower, however, they are still capable of dealing damage. After being held for a period of time it will break and lose its power permanently. They can be found in various locations but are not as abundant as the Holy Candle.
Henry Townshend discovers the existence of the medallions, along with the Holy Candle, when he is given a red letter from Joseph Schreiber under Room 302's front door. Joseph comments that it seems to repel unholy energy when it's worn.
- If examined closely, the medallion depicts an image of a mother and child: "Saint Alessa." The exact picture is featured in a chapel found in Silent Hill 3.