The Cleopatra Key is an obtainable key in Silent Hill: Origins, stuck inside of a locked washing machine in the laundry room of Riverside Motel. To retrieve it, Travis Grady must solve a puzzle involving the machine. The key unlocks the door to the Cleopatra Room.
- Cleopatra was a ruler of ancient Egypt, known for her beauty. The key tag shows a picture of a snake, and history has believed Cleopatra to be bitten on the arm and killed by a snake, and Shakespeare portrayed her as a woman holding a snake against her breasts in his Antony and Cleopatra tragedy.