Dr. Chloe Zane was a psychiatrist at St. Maria's Institute (now St. Maria's Monastery) in Silent Hill: Downpour.
Biography
Chloe dealt with evaluating each new patient's mental state, suggesting appropriate courses of action and evaluating their progress. The methods she suggested in order to deviate from these mental issues included electro-shock therapy and full frontal lobotomy, sometimes resulting in the death of the patient.
It's unknown what happened to Chloe, or when and why the institute was converted into a monastery.