Silent Hill 2
The song plays when James Sunderland sees Maria being stabbed by two Pyramid Heads in Lakeview Hotel and realizes Pyramid Head's symbolism. The song continues throughout the final boss fight against the two Pyramid Heads and stops once both of the bosses impale themselves with their own spears.
Silent Hill film
The song is heard in the film adaptation of the first game when Rose Da Silva is in the bowling alley and she discovers what she thought to be a crucified corpse is actually alive. The audio stops when Rose meets the Grey Children.